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Oxycodone is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the opium poppy. It is a moderately potent opioid analgesic, generally indicated for the relief of moderate to severe pain. Oxycodone is available as single-ingredient medication in immediate release and controlled release(intended to be taken every 12 hours). A 2006 review found that controlled-release oxycodone is comparable to instant release oxycodone, morphine, and hydromorphone in the management of moderate to severe cancer pain, with fewer side effects than morphine.